Fluid Flow Impacts Endothelial-Monocyte Interactions in a Model of Vascular Inflammatory Fibrosis
Isabelle Linares, Kaihua Chen, Ava Saffren, Mehran Mansouri, Vinay V. Abhyankar, Benjamin L. Miller, Stefano Begolo, Hani A. Awad, James L. McGrath
This study shows that adding physiological flow to a human tendon-on-a-chip model increases endothelial activation and monocyte infiltration, highlighting the role of flow in immune cell interactions during inflammation.
Scientific Reports · Jan 25, 2025Peer-reviewedBioengineering