Genome-wide CRISPRi screening reveals regulators of Alzheimee's tau pathology shared between exosomal and vesicle-free tau seeds.
Juan Carlos Polanco, Yevhen A. Akimov, Avinash Fernandes, Gabriel Rhys Hand, Adam Briner, Marloes van Roijen, Giuseppe Balistreri, Jürgen Götz
This study uses CRISPRi screening to identify cellular regulators that restrict both exosomal and vesicle-free tau seeding in Alzheimer's disease.
Life Science Alliance · Oct 31, 2022Peer-reviewedNeuroscience