Author

Yevhen A. Akimov

University of HelsinkiORCID 0000-0003-0413-2564Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Tero A. AittokallioiD· 2 shared Adam BrineriD· 1 shared Avinash Fernandes· 1 shared Daria R. BulanovaiD· 1 shared Gabriel Rhys Hand· 1 shared Giuseppe BalistreriiD· 1 shared Juan Carlos PolancoiD· 1 shared Jürgen GötziD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Tero A. AittokallioORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedOct 8, 2026

Estimating the completeness of large-scale single-cell sequencing projects

Mitro Miihkinen, Yidian Chu, Sara Vakkilainen…·Tero A. Aittokallio

This paper estimates the completeness of large-scale single-cell sequencing projects using ecological richness metrics applied to cellular diversity data.

DOI 10.1038/s41467-026-78221-5

humanscRNA-seq

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NeuroscienceLife Science AlliancePeer-reviewedOct 31, 2022

Genome-wide CRISPRi screening reveals regulators of Alzheimee's tau pathology shared between exosomal and vesicle-free tau seeds.

Juan Carlos Polanco, Yevhen A. Akimov, Avinash Fernandes…·Jürgen Götz

This study uses CRISPRi screening to identify cellular regulators that restrict both exosomal and vesicle-free tau seeding in Alzheimer's disease.

12 citations

humanCRISPR screen

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BioinformaticsMolecular Systems BiologyPeer-reviewedMar 1, 2020

Improved detection of differentially represented DNA barcodes for high-throughput lineage phenomics

Yevhen A. Akimov, Daria R. Bulanova, Sanna H. Timonen…·Tero A. Aittokallio

The paper introduces an improved algorithm for detecting differentially responding lineages in DNA barcoding experiments, showing higher accuracy than RNA-seq methods.

19 citations

humanDNA methylation

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