Damage sensing through TLR9 Regulates Inflammatory and Antiviral Responses During Influenza Infection
Jooyoung Kim, Yifan Yuan, Karen Agaronyan, Amy Zhao, Victoria Wang, David M. Gau, Nicholas Toosi, Gayatri Gupta, Heran Essayas, Ayelet Kaminski, John McGovern, Sheeline Yu, Samuel Woo, Chris Lee, Shifa Gandhi, , Lokesh Sharma
This study shows that TLR9 sensing of tissue damage during influenza infection promotes inflammation and antiviral responses, but its absence leads to impaired viral clearance and prolonged lung injury.
Mucosal Immunology · Jan 28, 2025Peer-reviewedImmunology