Yifan Yuan

This study uses time-resolved single-cell RNA sequencing in mice to show age and sex influence immune responses and viral disease severity through altered gene expression and inflammation.

This study identifies VEGF-D as a key factor in maintaining lung vascular integrity during acute lung injury using single-cell RNA sequencing and functional assays.

The paper identifies ADM/RAMP2 signaling as enhancing endothelial cell homeostasis and barrier integrity, synergistically with shear stress, using in vitro models and functional assays.

This study shows that TLR9 sensing of tissue damage during influenza infection promotes inflammation and antiviral responses, but its absence leads to impaired viral clearance and prolonged lung injury.

The paper identifies cell-to-cell communication between mesothelial cells and alveolar tuft cells that regulates lung regeneration after pneumonectomy.