Vagus nerve stimulation limits colonic inflammation through distinct neuroimmune circuitry shaped by inflammatory history
Kristina Sanchez, Jungjae Park, Emmy Xue Yun Tay, Gatha Pore, Abigail Wagner, Sarah Lee, Jane Li, Ayra Mirza, Mélanie G. Gareau, Colin Reardon
This paper shows that vagus nerve stimulation reduces colonic inflammation in mice, but only if the colon has a history of prior inflammation.
bioRxiv · May 28, 2026 · PreprintImmunology