Histone deacetylase 6 inhibition promotes microtubule acetylation and facilitates autophagosome-lysosome fusion in dystrophin-deficient mdx mice
A. Agrawal, E. L. Clayton, C. L. Cavazos, B. A. Clayton, G. G. Rodney
This study shows that inhibiting HDAC6 increases tubulin acetylation and autophagosome-lysosome fusion in dystrophin-deficient mdx mice, improving muscle function and reducing damage.
bioRxiv · Apr 29, 2022Cell Biology