G. G. Rodney

A Deep Redox Proteome Profiling Workflow and Its Application to Skeletal Muscle of a Duchene Muscular Dystrophy Model

The paper introduces a deep redox proteome profiling workflow and applies it to skeletal muscle from mdx mice, revealing increased thiol oxidation and pathway-specific effects.

Histone deacetylase 6 inhibition promotes microtubule acetylation and facilitates autophagosome-lysosome fusion in dystrophin-deficient mdx mice

This study shows that inhibiting HDAC6 increases tubulin acetylation and autophagosome-lysosome fusion in dystrophin-deficient mdx mice, improving muscle function and reducing damage.