Balanced Input from the tRNA Prenyltransferase MiaA Controls the Stress Resistance and Virulence Potential of Extraintestinal Pathogenic Escherichia coli
M. G. Blango, B. A. Fleming, W. M. Kincannon, A. Tran, A. J. Lewis, C. W. Russell, Q. Zhou, L. M. Baird, J. R. Brannon, C. J. Beebout, V. Bandarian, M. Hadjifraniskou, M. T. Howard, M. A. Mulvey
This study shows that MiaA, but not MiaB, is critical for the fitness and virulence of ExPEC, and that stress can alter MiaA expression to affect translation and proteome composition.
bioRxiv · Feb 2, 2021 · PreprintMicrobiology