Author

B. B. Au-Yeung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Eggert· 2 shared A. Weiss· 1 shared C. D. Scharer· 1 shared C. Scharer· 1 shared K. Salaita· 1 shared W. M. Zinzow-Kramer· 1 shared W. Zinzow-Kramer· 1 shared Y. Hu· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

J. Eggert

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2 papers

Recent·Most cited

Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness

J. Eggert, W. Zinzow-Kramer, Y. Hu, Y.-L. Tsai, A. Weiss, K. Salaita, C. Scharer, B. B. Au-Yeung

The study shows that prolonged TCR signaling from self-antigens in naive CD8 T cells reduces their responsiveness to foreign antigens through gene expression changes and negative regulators like Sts1 and Cbl-b.

bioRxiv · Jan 27, 2023Immunology

Strong basal/tonic TCR signals are associated with negative regulation of naive CD4+ T cells

W. M. Zinzow-Kramer, J. Eggert, C. D. Scharer, B. B. Au-Yeung

The paper investigates the relationship between strong tonic TCR signals and negative regulation in naive CD4+ T cells, finding that high tonic signals correlate with hypo-responsiveness and increased expression of negative regulators.

bioRxiv · Apr 20, 2022Immunology