Author

C. Scharer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Corrado· 1 shared A. Ley· 1 shared A. Weiss· 1 shared B. B. Au-Yeung· 1 shared C. J. Joyner· 1 shared C. Tipton· 1 shared D. Nguyen· 1 shared D. Roberts· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Corrado

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2 papers

Recent·Most cited

Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness

J. Eggert, W. Zinzow-Kramer, Y. Hu, Y.-L. Tsai, A. Weiss, K. Salaita, C. Scharer, B. B. Au-Yeung

The study shows that prolonged TCR signaling from self-antigens in naive CD8 T cells reduces their responsiveness to foreign antigens through gene expression changes and negative regulators like Sts1 and Cbl-b.

bioRxiv · Jan 27, 2023Immunology

Maturation of Human Long-lived Plasma Cells Results in Resistance to Apoptosis by Transcriptional and Epigenetic Regulation

C. J. Joyner, A. Ley, D. Nguyen, M. Ali, A. Corrado, C. Tipton, C. Scharer, T. Mi, M. C. Woodruff, J. Hom, J. M. Boss, M. Duan, G. Gibson, D. Roberts, J. Andrews, , F. E.-H. Lee

This study shows human blood ASCs undergo transcriptional and epigenetic changes in the BM microniche to become apoptotic-resistant LLPC.

bioRxiv · May 22, 2021 · PreprintImmunology