Author

B. C. Hacker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. Rafat· 3 shared S. E. Martello· 3 shared E. J. Lin· 2 shared A. Adamo· 1 shared A. D'Amore· 1 shared A. Hawkes· 1 shared A. J. Walker· 1 shared A. M. Questell· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCancer Biology

M. Rafat

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Author profile →

3 papers

Recent·Most cited

Ultrafast Power Doppler Ultrasound Enables Longitudinal Tracking of Vascular Changes that Correlate with Immune Response After Radiotherapy

S. E. Martello, J. Xia, J. Kusunose, B. C. Hacker, M. A. Mayeaux, E. J. Lin, A. Hawkes, A. Singh, C. F. Caskey, M. Rafat

This paper uses ultrafast power Doppler ultrasound to track vascular changes in tumors after radiotherapy, showing correlation with immune response.

bioRxiv · Aug 4, 2023Cancer Biology

Irradiated Mammary Spheroids Elucidate Mechanisms of Macrophage-Mediated Breast Cancer Recurrence

B. C. Hacker, D. C. Herman, E. J. Lin, A. M. Questell, S. E. Martello, R. J. Hedges, A. J. Walker, M. Rafat

The paper develops a spheroid model to study macrophage-mediated breast cancer recurrence and identifies IL-6 signaling as a key mechanism.

bioRxiv · Jul 24, 2022Cancer Biology

Mammary Tissue-Derived Extracellular Matrix Hydrogels Reveal the Role of Irradiation in Driving a Pro-Tumor and Immunosuppressive Microenvironment

T. Zhu, S. M. Alves, A. Adamo, X. Wen, K. C. Corn, A. Shostak, S. Johnson, N. D. Shaub, S. E. Martello, B. C. Hacker, A. D'Amore, R. Bardhan, M. Rafat

This study shows that irradiated mammary tissue ECM hydrogels promote TNBC cell proliferation, invasion, and immunosuppression by altering ECM composition and macrophage polarization.

bioRxiv · May 16, 2022Cancer Biology