Cancer BiologybioRxiv
Inhibition of mitochondrial dynamics preferentially targets pancreatic cancer cells with enhanced tumorigenic and invasive potential
S. Courtois, B. de Luxan-Delgado, L. Penin-Peyta…·P. Sancho
This study shows that inhibiting mitochondrial fission with mDivi-1 selectively kills pancreatic cancer stem cells by causing mitochondrial dysfunction and energy crisis.
DOI 10.3390/cancers13040698