Integrin Affinity Modulation Critically Regulates Atherogenic Endothelial Activation in vitro and in vivo
Z. Al Yafeai, J. M. Peretik, B. H. Pearson, U. Bhattarai, D. Wang, B. G. Petrich, A. W. Orr
This study shows that integrin affinity modulation is critical for endothelial activation in response to atheroprone hemodynamics and oxidized lipoproteins, with talin1 L325R mutations impairing this process.
bioRxiv · Feb 14, 2020Cell Biology