Author

Z. Al Yafeai

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. W. Orr· 1 shared B. G. Petrich· 1 shared B. H. Pearson· 1 shared D. Wang· 1 shared J. M. Peretik· 1 shared U. Bhattarai· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

A. W. Orr

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1 paper

Recent·Most cited

Cell BiologybioRxivFeb 14, 2020

Integrin Affinity Modulation Critically Regulates Atherogenic Endothelial Activation in vitro and in vivo

Z. Al Yafeai, J. M. Peretik, B. H. Pearson…·A. W. Orr

This study shows that integrin affinity modulation is critical for endothelial activation in response to atheroprone hemodynamics and oxidized lipoproteins, with talin1 L325R mutations impairing this process.

DOI 10.1016/j.matbio.2020.10.006

mousegenetic perturbation / CRISPR

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