B. J. Y. Tan

The paper introduces HIV-Tocky, a reporter system using a fluorescent Timer protein to visualize HIV-1 provirus expression dynamics and identifies two latent subsets of proviruses.

This study uses a novel mouse model to analyze how checkpoint blockade affects tumour-reactive T cell activation dynamics at the single-cell level.

The paper demonstrates that clonality values of BLV-infected cells in blood can reliably detect Enzootic Bovine Leukosis and are useful for diagnostic testing.

The paper develops a new assay to evaluate latency-reversing agents by eliminating HIV-1 proviruses in a long-term cell culture system.

This study uses single-cell RNA-Seq and TCR-Seq to show HTLV-1-infected T-cells transition into highly activated ATL cells with Treg signatures and upregulated HLA class II, enabling immune evasion.