Author

R. P. Dyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

G. A. Weiss· 2 shared G. S. Salcedo· 2 shared H. M. Isoda· 2 shared S. Majumdar· 2 shared A. C. Chu· 1 shared A. D. Brideau-Andersen· 1 shared A. Jain· 1 shared A. M. Santos· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

G. A. Weiss

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Author profile →

2 papers

Recent·Most cited

Predicting COVID-19 Severity with a Specific Nucleocapsid Antibody plus Disease Risk Factor Score

S. Sen, E. C. Sanders, K. N. Gabriel, B. M. Miller, H. M. Isoda, G. S. Salcedo, J. E. Garrido, R. P. Dyer, R. Nakajima, A. Jain, A.-M. Caldaruse, A. M. Santos, K. Bhuvan, D. F. Tifrea, J. L. Ricks-Oddie, , G. A. Weiss

This paper identifies an antibody epitope and a risk score to predict severe COVID-19 outcomes with high specificity.

bioRxiv · Oct 15, 2020Immunology

Reengineering the Specificity of the Highly Selective Clostridium botulinum Protease via Directed Evolution

R. P. Dyer, H. M. Isoda, G. S. Salcedo, G. Speciale, M. H. Fletcher, L. Q. Le, Y. Liu, S. Z. Malik, E. J. Vazquez-Cintron, A. C. Chu, D. C. Rupp, B. Jacky, T. T. Nguyen, L. E. Steward, S. Majumdar, , G. A. Weiss

This study uses directed evolution to reengineer the BoNT/A protease to target SNAP23, improving its cleavage specificity and catalytic efficiency for therapeutic applications.

bioRxiv · Sep 29, 2020Biochemistry