Author

B. K. Chan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

P. E. Turner· 2 shared C. Gougat-Barbera· 1 shared C. Y. Leung· 1 shared E. Vasen· 1 shared J. Gurney· 1 shared J. S. Griffin· 1 shared J. S. Weitz· 1 shared L. Pradier· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersEvolutionary Biology

P. E. Turner

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Author profile →

3 papers

Recent·Most cited

Decay and damage of therapeutic phage OMKO1 by environmental stressors

M. Blazanin, W. T. Lam, E. Vasen, B. K. Chan, P. Turner

This study examines how environmental stressors affect the decay and potency of therapeutic phage OMKO1, finding it tolerant to saline but vulnerable to heat and urea.

bioRxiv · Jul 3, 2021Microbiology

Phage steering of antibiotic-resistance evolution in the bacterial pathogen Pseudomonas aeruginosa

J. Gurney, L. Pradier, J. S. Griffin, C. Gougat-Barbera, B. K. Chan, P. E. Turner, O. Kaltz, M. E. Hochberg

This study shows that phage OMKO1 can reduce antibiotic resistance in Pseudomonas aeruginosa both in vitro and in vivo, by selecting for antibiotic sensitivity and phage resistance.

bioRxiv · Dec 10, 2019Evolutionary Biology

Quantitative Models of Phage-Antibiotics Combination Therapy

R. A. Rodriguez-Gonzalez, C. Y. Leung, B. K. Chan, P. E. Turner, J. S. Weitz

This study develops a nonlinear population dynamics model to evaluate phage-antibiotic combination therapy for MDR bacteria, showing improved efficacy with sub-inhibitory antibiotic concentrations and innate immune interactions.

bioRxiv · Nov 8, 2019Microbiology