Author

M. E. Hochberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

R. J. Noble· 2 shared B. K. Chan· 1 shared C. Gougat-Barbera· 1 shared C. Le Sueur· 1 shared C. Roumestand· 1 shared J. Gurney· 1 shared J. S. Griffin· 1 shared J. T. Burley· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

R. J. Noble

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Author profile →

3 papers

Recent·Most cited

Paracrine behaviors arbitrate parasite-like interactions between tumor subclones

R. J. Noble, V. Walther, C. Roumestand, U. Hibner, M. E. Hochberg, P. Lassus

The paper shows that in vitro, one tumor subclone benefits from the presence of another by farming it through paracrine metabolites, enhancing its growth while reducing the loser's growth.

bioRxiv · Dec 14, 2020Cancer Biology

When, why and how clonal diversity predicts future tumour growth

R. J. Noble, J. T. Burley, C. Le Sueur, M. E. Hochberg

This study uses a spatial computational model to show how clonal diversity correlates with tumour growth rate under specific conditions and highlights its limitations compared to conventional biomarkers.

bioRxiv · Dec 17, 2019Cancer Biology

Phage steering of antibiotic-resistance evolution in the bacterial pathogen Pseudomonas aeruginosa

J. Gurney, L. Pradier, J. S. Griffin, C. Gougat-Barbera, B. K. Chan, P. E. Turner, O. Kaltz, M. E. Hochberg

This study shows that phage OMKO1 can reduce antibiotic resistance in Pseudomonas aeruginosa both in vitro and in vivo, by selecting for antibiotic sensitivity and phage resistance.

bioRxiv · Dec 10, 2019Evolutionary Biology