Author

B. K. Coombes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:mouse· 1

Frequent Co-Authors

C. N. Tsai· 2 shared E. D. Brown· 2 shared C. MacNair· 1 shared H. Andrews-Polymenis· 1 shared J. Magolan· 1 shared J. N. Perry· 1 shared J. W. Johnson· 1 shared M. J. Ellis· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

C. N. Tsai

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2 papers

Recent·Most cited

Screening under infection-relevant conditions reveals chemical sensitivity in multidrug-resistant invasive non-typhoidal Salmonella (iNTS)

C. N. Tsai, M.-A. Massicotte, C. MacNair, J. N. Perry, E. D. Brown, B. K. Coombes

This study identifies chemical sensitivities in multidrug-resistant iNTS Salmonella under infection-relevant conditions, revealing potential drug targets.

bioRxiv · Sep 16, 2022Microbiology

A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium

M. J. Ellis, C. N. Tsai, J. W. Johnson, S. French, W. Elhenawy, S. Porwollik, H. Andrews-Polymenis, M. McClelland, J. Magolan, B. K. Coombes, E. D. Brown

The paper identifies antibacterial compounds effective against intracellular Salmonella Typhimurium through macrophage-based screens and shows metergoline enhances activity by perturbing the bacterial outer membrane.

bioRxiv · Aug 2, 2018Microbiology