Author

M. McClelland

Primary ORCID profile (0000-0003-1788-9347 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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M. McClellandiD1 paper

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Porwollik· 2 shared B. K. Coombes· 1 shared C. N. Tsai· 1 shared E. D. Brown· 1 shared E. R. Hughes· 1 shared F. Faber· 1 shared H. Andrews-Polymenis· 1 shared H. L. Andrews-Polymenis· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

S. Porwollik

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2 papers

Recent·Most cited

Byproducts of inflammatory radical metabolism provide transient nutrient niches for microbes in the inflamed gut

L. Spiga, M. G. Winter, M. Muramatsu, V. Rojas, R. Chanin, W. Zhu, E. R. Hughes, S. Taylor, F. Faber, S. Porwollik, T. Carvalho, T. Qin, R. Santos, H. L. Andrews-Polymenis, M. McClelland, S. E. Winter

The paper investigates how inflammatory radicals generate tartaric acid isomers, which serve as transient nutrients for gut pathogens in murine models.

bioRxiv · Dec 8, 2023 · PreprintMicrobiology

A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium

M. J. Ellis, C. N. Tsai, J. W. Johnson, S. French, W. Elhenawy, S. Porwollik, H. Andrews-Polymenis, M. McClelland, J. Magolan, B. K. Coombes, E. D. Brown

The paper identifies antibacterial compounds effective against intracellular Salmonella Typhimurium through macrophage-based screens and shows metergoline enhances activity by perturbing the bacterial outer membrane.

bioRxiv · Aug 2, 2018Microbiology