Regulation of Store-Operated Ca2+ Entry by IP3 Receptors Independent of Their Ability to Release Ca2+
P. Chakraborty, B. K. Deb, V. Arige, T. Musthafa, S. Malik, D. I. Yule, C. W. Taylor, G. Hasan
The paper shows IP3Rs regulate neuronal SOCE through IP3 binding, independent of Ca2+ release, by enhancing STIM1-Orai1 association.
bioRxiv · Apr 12, 2022Cell Biology