Author

B. M. Fernandez-Ciruelos

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Microbiology· 1

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

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A. Adhav· 1 shared A. Jirgensons· 1 shared A. Marina· 1 shared A. Ritchie-Martinez· 1 shared F. Taverne· 1 shared J. M. Wells· 1 shared M. Albanese· 1 shared N. Velikova· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperMicrobiology

A. Adhav

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1 paper

Recent·Most cited

MicrobiologyMicrobiology SpectrumPeer-reviewedAug 6, 2024

Repurposing Hsp90 inhibitors as antimicrobials targeting two-component systems identifies compounds leading to loss of bacterial membrane integrity

B. M. Fernandez-Ciruelos, M. Albanese, A. Adhav…·J. M. Wells

This study repurposes Hsp90 inhibitors as antimicrobials targeting bacterial two-component systems, finding that DPP analogues disrupt bacterial membranes and show antimicrobial activity against Gram-positive bacteria.

DOI 10.1128/spectrum.00146-24

bacteria (other)experimental assay

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