Author

B. M. Petersen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

T. A. Whitehead· 3 shared E. R. Rhodes· 2 shared A. C. Leonard· 1 shared A. J. Friedman· 1 shared A. Walker· 1 shared B. J. Dekosky· 1 shared C. Haas· 1 shared E. Ayala· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBiochemistry

T. A. Whitehead

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Author profile →

3 papers

Recent·Most cited

An integrated technology for quantitative wide mutational scanning of human antibody Fab libraries

B. M. Petersen, M. Kirby, K. Chrispens, O. Irvin, I. Strawn, C. Haas, A. Walker, Z. T. Baumer, S. Ulmer, E. Ayala, O. Irvin, E. R. Rhodes, J. Guthmiller, P. J. Steiner, T. A. Whitehead

The paper introduces MAGMA-seq, a technology for quantitative analysis of antibody sequence-function relationships, demonstrating its application in mapping antibody development pathways and identifying binding determinants.

Nature Communications · May 10, 2024Peer-reviewedBiochemistry

Rationalizing diverse binding mechanisms to the same protein fold: in-sights for ligand recognition and biosensor design

A. C. Leonard, A. J. Friedman, R. Chayer, B. M. Petersen, J. Kaar, M. R. Shirts, T. A. Whitehead

This study analyzes two engineered biosensors based on PYR1 to recognize different ligands, revealing binding mechanisms and computational methods for biosensor design.

bioRxiv · Mar 25, 2024Bioengineering

Regulatory approved monoclonal antibodies contain framework mutations predicted from human antibody repertoires

B. M. Petersen, S. A. Ulmer, E. R. Rhodes, M. F. Gutierrez Gonzalez, B. J. Dekosky, K. G. Sprenger, T. A. Whitehead

The paper predicts framework mutations in therapeutic monoclonal antibodies using natural human antibody repertoires, showing potential to improve antibody properties and reduce immunogenicity.

bioRxiv · Jun 22, 2021Immunology