Author

B. Manadas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

S. I. Anjo· 3 shared M. Graos· 2 shared A. Castander-Olarieta· 1 shared A. d. Mendonca· 1 shared A. Gomes· 1 shared A. Verdelho· 1 shared C. Domingues· 1 shared C. Januario· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBiochemistry

S. I. Anjo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mimicking physiological stiffness or oxygen levels in vitro reorganizes mesenchymal stem cells machinery toward a more naive phenotype

I. Caramelo, V. m. Mendes, C. Domingues, S. I. Anjo, M. Geraldo, C. M. P. Cardoso, M. Graos, B. Manadas

This paper shows that culturing MSCs on soft substrates or under low oxygen levels alters their proteome, promoting a more naive phenotype by affecting redox homeostasis, protein chaperones, and translational complexity.

bioRxiv · Jun 11, 2024 · PreprintCell Biology

Unmasking Hidden Systemic Effects of Neurodegenerative Diseases: A Two-Pronged Approach to Biomarker Discovery

S. I. Anjo, M. Rosado, I. Baldeiras, A. Gomes, D. Pires, C. Santa, J. Pinto, C. Januario, I. Santana, A. Verdelho, A. d. Mendonca, M. Castelo-Branco, B. Manadas

This paper evaluates HMW fractionation as a complementary proteomics approach to identify serum biomarkers for neurodegenerative diseases, showing improved discrimination compared to direct serum analysis.

bioRxiv · Nov 23, 2023 · PreprintBiochemistry

Thermopriming-associated proteome and sugar content responses in Pinus radiata embryogenic tissue

A. Castander-Olarieta, C. Pereira, V. Mendes, S. Correia, B. Manadas, J. Canhoto, I. A. Montalban, P. Moncalean

This study examines proteome and sugar content changes in Pinus radiata embryogenic tissue after heat treatment to understand thermopriming mechanisms.

bioRxiv · May 17, 2022Plant Biology

A generic normalization method for proper quantification in untargeted proteomics screening

S. I. Anjo, I. Simoes, P. Castanheira, M. Graos, B. Manadas

This paper introduces a normalization method using recombinant proteins as internal standards for untargeted label-free proteomics, showing comparable performance to existing methods while preserving proteome changes between groups.

bioRxiv · Apr 25, 2018Biochemistry