Cholesteryl Hemiazelate Induces Lysosome Dysfunction and Exocytosis in Macrophages
N. Domingues, R. D. A. Calado, P. Brito, R. Matthiesen, J. Ramalho, M. I. L. Soares, T. Pereira, L. Oliveira, J. Vicente, L. H. Wong, S. M. Cho, I. Simoes, J. Sampaio, C. Klose, M. A. Surma, , O. V. Vieira
This study identifies cholesteryl hemiazelate as a cause of lysosome dysfunction and exocytosis in macrophages, contributing to atherosclerosis.
bioRxiv · Jan 5, 2021 · PreprintCell Biology