Author

B. N. Dubey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Approach:biophysical modeling· 2 Organism:C. elegans· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

T. Schirmer· 4 shared R. Boehm· 3 shared S. Hiller· 3 shared U. Jenal· 3 shared A. Kaczmarczyk· 2 shared C. von Arx· 2 shared A. M. Hempel· 1 shared E. Agustoni· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersBiochemistry

T. Schirmer

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4 papers

Recent·Most cited

High-resolution crystal structure of a metabolic switch protein in a complex with monomeric c-di-GMP reveals a potential mechanism for c-di-GMP dimerization

B. N. Dubey, V. Shyp, G. Fucile, U. Jenal, T. Schirmer

The paper reports a high-resolution crystal structure of a SmbA mutant complex with monomeric c-di-GMP, revealing loop 7's role in c-di-GMP dimerization and SmbA function.

bioRxiv · Jul 30, 2022Biochemistry

Intermediaries in phosphotransfer: structural features discriminating hybrid histidine kinase Rec domains from response regulator homologs

M. Bruederlin, R. Boehm, F. Fadel, S. Hiller, T. Schirmer, B. N. Dubey

The paper structures and analyzes the CckARec domain from C. crescentus to distinguish it from RR Rec domains, highlighting structural differences in phosphoryl-binding and absence of allosteric changes.

bioRxiv · Jun 3, 2022Biochemistry

Hybrid histidine kinase activation by cyclic di-GMP- mediated domain liberation

B. N. Dubey, E. Agustoni, R. Boehm, A. Kaczmarczyk, F. Mangia, C. von Arx, U. Jenal, S. Hiller, I. Plaza-Menacho, T. Schirmer

This study reveals how c-di-GMP regulates ShkA, a hybrid histidine kinase in Caulobacter crescentus, by inducing domain dissociation and allosteric activation.

bioRxiv · Jun 22, 2019Biochemistry

Precise transcription timing by a second-messenger drives a bacterial G1/S cell cycle transition

A. Kaczmarczyk, A. M. Hempel, C. von Arx, R. Boehm, B. N. Dubey, J. Nesper, T. Schirmer, S. Hiller, U. Jenal

This study identifies c-di-GMP as a second messenger that regulates the G1/S transition in Caulobacter crescentus by modulating ShkA and TacA activity.

bioRxiv · Jun 20, 2019Microbiology