Author

I. Plaza-Menacho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 2 Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Kaczmarczyk· 1 shared A. Martin-Hurtado· 1 shared B. N. Dubey· 1 shared C. von Arx· 1 shared E. Agustoni· 1 shared F. Mangia· 1 shared I. M. Munoz· 1 shared J. M. Contreras· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Kaczmarczyk

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2 papers

Recent·Most cited

An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function

N. Cuesta, J. M. Contreras, J. Sanchez-Waldermer, P. Soriano-Maldonado, A. Martin-Hurtado, I. M. Munoz, M. Llimargas, J. Munoz, I. Plaza-Menacho

This paper identifies an allosteric switch between c-Src's activation loop and a c-terminal phospho-motif that regulates auto-phosphorylation, enzyme specificity, and non-catalytic function.

bioRxiv · Oct 16, 2022Biochemistry

Hybrid histidine kinase activation by cyclic di-GMP- mediated domain liberation

B. N. Dubey, E. Agustoni, R. Boehm, A. Kaczmarczyk, F. Mangia, C. von Arx, U. Jenal, S. Hiller, I. Plaza-Menacho, T. Schirmer

This study reveals how c-di-GMP regulates ShkA, a hybrid histidine kinase in Caulobacter crescentus, by inducing domain dissociation and allosteric activation.

bioRxiv · Jun 22, 2019Biochemistry