Author

B. N. Lambrecht

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

C. De Wolf· 2 shared H. Hammad· 2 shared J. Deckers· 2 shared M. Vanheerswynghels· 2 shared N. Debeuf· 2 shared S. Lameire· 2 shared A. Choi· 1 shared A. Garcia-Sastre· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

C. De Wolf

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders

N. Debeuf, S. Lameire, M. Vanheerswynghels, J. Deckers, C. De Wolf, W. Toussaint, R. Verbeke, K. Verstaen, H. Hammad, S. Vanhee, B. N. Lambrecht

The paper develops a method to select optimal TCR transgenic clones using single-cell RNA sequencing and TCR repertoire analysis, enabling the generation of CORSET8 mice specific to SARS-CoV-2 Spike protein.

bioRxiv · Mar 27, 2024Immunology

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike

S. De Cae, I. Van Molle, L. van Schie, S. R. Shoemaker, J. Deckers, N. Debeuf, S. Lameire, W. Nerinckx, K. Roose, D. Fijalkowska, S. Devos, A.-S. Desmet, J. C. Zavala Marchan, T. Venneman, G. H. Ghassabeh, , B. Schepens

The paper identifies ultrapotent SARS-CoV-2-neutralizing nanobodies that bind a conserved epitope on the spike protein, showing therapeutic efficacy in hamsters.

bioRxiv · Mar 10, 2023 · PreprintMicrobiology

Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

S. Jangra, J. De Vrieze, A. Choi, R. Rathnasinghe, G. Laghlali, A. Uvyn, S. Van Herck, L. Nuhn, K. Deswarte, Z. Zhong, N. Sanders, S. Lienenklaus, S. David, S. Strohmeier, F. Amanat, , M. Schotsaert

This paper demonstrates that a novel TLR7/8 agonist adjuvant enables single-shot protection against SARS-CoV-2 and influenza in mice using recombinant spike protein and inactivated vaccines.

bioRxiv · Oct 23, 2020Microbiology