Author

S. R. Shoemaker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Organism:mouse· 1

Frequent Co-Authors

S. Marqusee· 4 shared A. W. Nguyen· 2 shared C.-L. Hsieh· 2 shared H. T. Hobbs· 2 shared J. A. Maynard· 2 shared J. S. McLellan· 2 shared S. M. Costello· 2 shared A. L. Bohanon· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersBiochemistry

S. Marqusee

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Identification of a conserved neutralizing epitope present on spike proteins from all highly pathogenic coronaviruses

Y. Huang, A. W. Nguyen, C.-L. Hsieh, R. Silva, O. S. Olaluwoye, R. Wilen, T. S. Kaoud, L. R. Azouz, A. N. Qerqez, K. C. Le, A. L. Bohanon, A. M. DiVenere, Y. Liu, D. Amengor, S. R. Shoemaker, , J. A. Maynard

The paper identifies a conserved neutralizing epitope on the S2 domain of SARS-CoV, SARS-CoV-2, and MERS-CoV spike proteins that is targeted by antibody 3A3.

eLife · Mar 21, 2023Peer-reviewedBiochemistry

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike

S. De Cae, I. Van Molle, L. van Schie, S. R. Shoemaker, J. Deckers, N. Debeuf, S. Lameire, W. Nerinckx, K. Roose, D. Fijalkowska, S. Devos, A.-S. Desmet, J. C. Zavala Marchan, T. Venneman, G. H. Ghassabeh, , B. Schepens

The paper identifies ultrapotent SARS-CoV-2-neutralizing nanobodies that bind a conserved epitope on the spike protein, showing therapeutic efficacy in hamsters.

bioRxiv · Mar 10, 2023 · PreprintMicrobiology

Saturation mutagenesis of a predicted ancestral Syk-family kinase

H. T. Hobbs, N. H. Shah, S. R. Shoemaker, J. F. Amacher, S. Marqusee, J. Kuriyan

The paper generates a bacterial-expressible Syk-family kinase via ancestral sequence reconstruction and uses deep mutational scanning to identify functional mutations.

bioRxiv · Apr 24, 2022Biochemistry

Discovery of a carbonic anhydrase-Rubisco complex within the alpha-carboxysome

C. Blikstad, E. J. Dugan, T. G. Laughlin, J. B. Turnsek, M. D. Liu, S. R. Shoemaker, N. Vogiatzi, J. P. Remis, D. F. Savage

This study identifies the structural basis of carbonic anhydrase incorporation into carboxysomes by showing direct interaction with Rubisco via an N-terminal domain.

bioRxiv · Nov 5, 2021 · PreprintBiochemistry

The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes

S. M. Costello, S. R. Shoemaker, H. T. Hobbs, A. W. Nguyen, C.-L. Hsieh, J. A. Maynard, J. S. McLellan, J. E. Pak, S. Marqusee

The paper identifies an alternative open-trimer conformation of the SARS-CoV-2 spike ectodomain that exposes novel epitopes and is modulated by temperature, binding, and sequence variants.

bioRxiv · Jul 11, 2021Biophysics