Author

D. Fijalkowska

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

N. Callewaert· 3 shared B. Schepens· 2 shared C. Lonigro· 2 shared H. Demol· 2 shared J. C. Zavala Marchan· 2 shared J. Neyts· 2 shared K. De Bosscher· 2 shared K. Roose· 2 shared

Activity by Year

2023-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

N. Callewaert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Yeast-based production platform for potent and stable heavy chain-only antibodies

C. Lonigro, H. Eeckhaut, R. A. Symakani, K. Roose, B. Schepens, K. Sedeyn, A.-S. De Smet, J. C. Zavala Marchan, P. Vanhaverbeke, S. Vanmarcke, K. Claes, S. De Cae, H. Demol, S. Devos, D. Fijalkowska, , N. Callewaert

This paper presents a yeast-based platform for producing stable and potent heavy chain-only antibodies, demonstrating its effectiveness with an anti-SARS-CoV-2 example.

bioRxiv · Mar 4, 2024 · PreprintMicrobiology

Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics

L. Delhaye, G. D. Moschonas, D. Fijalkowska, A. Verhee, D. De Sutter, T. Van de Steene, M. De Meyer, L. Van Moortel, K. De Bosscher, S. Eyckerman

The paper introduces a T2A split-link system for proximity labeling proteomics to improve control over enzymatic activity and expression levels, enhancing accuracy in identifying protein interactions.

bioRxiv · Nov 3, 2023Biochemistry

Crosstalk between the glucocorticoid and mineralocorticoid receptor boosts glucocorticoid-induced killing of multiple myeloma cells

D. Clarisse, S. Prekovic, P. Vlummens, E. Staessens, K. Van Wesemael, J. Thommis, D. Fijalkowska, G. Acke, W. Zwart, I. M. Beck, F. Offner, K. De Bosscher

This study shows that combining dexamethasone with spironolactone enhances myeloma cell killing through GR-MR crosstalk, with potential for dose reduction.

bioRxiv · May 10, 2023Cancer Biology

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike

S. De Cae, I. Van Molle, L. van Schie, S. R. Shoemaker, J. Deckers, N. Debeuf, S. Lameire, W. Nerinckx, K. Roose, D. Fijalkowska, S. Devos, A.-S. Desmet, J. C. Zavala Marchan, T. Venneman, G. H. Ghassabeh, , B. Schepens

The paper identifies ultrapotent SARS-CoV-2-neutralizing nanobodies that bind a conserved epitope on the spike protein, showing therapeutic efficacy in hamsters.

bioRxiv · Mar 10, 2023 · PreprintMicrobiology

N-glycosylation engineering in chimeric antigen receptor T cells enhances anti-tumor activity

E. De Bousser, N. Festjens, E. Plets, L. Meuris, L. Vuylsteke, D. Fijalkowska, A. Van Hecke, E. Wyseure, M. Goossens, L. De Pryck, S. Van den Bosch, S. De Munter, B. Vandekerckhove, N. Callewaert

This study shows that removing N-glycan modifications in CAR T cells improves their anti-tumor activity against solid tumors and lymphomas.

bioRxiv · Jan 23, 2023 · PreprintImmunology