Author

A.-S. Desmet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1

Frequent Co-Authors

X. Saelens· 2 shared A. Bath· 1 shared A. Maciejczuk· 1 shared B. N. Lambrecht· 1 shared B. Schepens· 1 shared B. Sodeik· 1 shared C. De Wolf· 1 shared C. Lonigro· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

X. Saelens

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Author profile →

2 papers

Recent·Most cited

MX2 restricts HIV-1 and herpes simplex virus type 1 by forming cytoplasmic biomolecular condensates that mimic nuclear pore complexes

G. D. Moschonas, L. Delhaye, R. Cooreman, F. Husers, A. Bath, D. De Sutter, E. Parthoens, A.-S. Desmet, A. Maciejczuk, H. Grzesik, S. Lippens, Z. Debyser, B. Sodeik, S. Eyckerman, X. Saelens

This study shows MX2 forms cytoplasmic condensates that mimic nuclear pore complexes to restrict HIV-1 and HSV-1 by trapping viral capsids and preventing nuclear entry.

bioRxiv · Jun 22, 2023 · PreprintMicrobiology

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike

S. De Cae, I. Van Molle, L. van Schie, S. R. Shoemaker, J. Deckers, N. Debeuf, S. Lameire, W. Nerinckx, K. Roose, D. Fijalkowska, S. Devos, A.-S. Desmet, J. C. Zavala Marchan, T. Venneman, G. H. Ghassabeh, , B. Schepens

The paper identifies ultrapotent SARS-CoV-2-neutralizing nanobodies that bind a conserved epitope on the spike protein, showing therapeutic efficacy in hamsters.

bioRxiv · Mar 10, 2023 · PreprintMicrobiology