The conserved centrosomal motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC).
M. J. Rale, B. Romer, B. P. Mahon, S. M. Travis, S. Petry
This study identifies γTuNA as a dimer that directly activates γTuRC to nucleate microtubules, opposing stathmin inhibition.
bioRxiv · Apr 11, 2022 · PreprintBiochemistry