Actin associates with actively elongating genes and binds directly to the Cdk9 subunit of P-TEFb
S. Kyheroinen, B. Prajapati, M. Sokolova, M. Schmitz, M. Geyer, M. K. Vartiainen
This study identifies a direct interaction between actin and Cdk9 in P-TEFb, showing actin binds to actively elongating genes and inhibits polymerization during transcription.
bioRxiv · Sep 6, 2023Cell Biology