B. Rissiek

Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system - no evidence for a role of neuronal P2X7 receptors in colitis

The paper investigates P2X7 receptor expression in the gut nervous system, finding it primarily in macrophages and glia rather than neurons, and suggests these cells mediate P2X7 effects in IBD.

A P2rx7 passenger mutation affects the vitality and function of immune cells in P2X4ko and other transgenic mice

The paper identifies a P2rx7 passenger mutation in 129-derived transgenic mice that affects T cell vitality and function, increasing sensitivity to NAD-induced cell death.