Author

B. Rosati

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Pradhan· 1 shared A. Van Der Velden· 1 shared C. K. Vorkas· 1 shared D. Carlson· 1 shared H. V. Han· 1 shared H. Xu· 1 shared J. Bean· 1 shared J.-B. Le Luduec· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Pradhan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of circulating CD8α+ NK cells during human Mycobacterium tuberculosis infection

N. Mehanna, A. Pradhan, R. Kaur, T. Kontopoulos, B. Rosati, D. Carlson, N.-K. Cheung, H. Xu, J. Bean, K. Hsu, J.-B. Le Luduec, C. K. Vorkas

The paper identifies CD8+ NK cells as a Mtb-responsive population with enhanced maturity and cytotoxicity in human TB infection, correlating with disease resistance.

bioRxiv · Apr 16, 2024 · PreprintImmunology

Propionyl-CoA carboxylase subunit B regulates anti-tumor T cells in a pancreatic cancer mouse model

H. V. Han, R. Efem, B. Rosati, K. Lu, S. Maimouni, Y.-P. Jiang, V. Montoya, A. Van Der Velden, W.-X. Zong, R. Z. Lin

This study identifies Pccb as a regulator of anti-tumor T cell activity in pancreatic cancer, showing that its deletion impairs T cell function and that PD-L1/PD1 blockade can restore T cell activity.

bioRxiv · Jul 24, 2023Cancer Biology

Simulation of the Gαq /Phospholipase Cβ1 Signaling Pathway Returns Differentiated PC12 Cells to a Stem-like State

O. Garwain, K. M. Pearce, L. Jackson, S. Carley, B. Rosati, S. S. Scarlata

The paper shows that reducing PLCβ1 or activating Gq to move PLCβ1 to the plasma membrane reverts differentiated PC12 cells to a stem-like state, characterized by morphology changes, proliferation, and expression of stem cell factors.

bioRxiv · Jan 6, 2020 · PreprintBiochemistry