Author

B. S. Trueeb

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

A. Breithaupt· 2 shared M. Beer· 2 shared N. Ebert· 2 shared V. Thiel· 2 shared A. Godel· 1 shared A. Kratzel· 1 shared A. Ohnemus· 1 shared A. Rauch· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

A. Breithaupt

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2 papers

Recent·Most cited

The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

T. Barut, N. J. Halwe, A. Taddeo, J. N. Kelly, J. Schön, N. Ebert, L. Ulrich, C. Devisme, S. Steiner, B. S. Trueeb, B. Hoffmann, I. B. Veiga, N. F. G. Leborgne, E. A. Moreira, A. Breithaupt, , V. Thiel

This study shows the spike gene determines replication, pathogenicity, and immune evasion of SARS-CoV-2 Omicron-BA.1 compared to Delta in cell cultures and animal models.

bioRxiv · Apr 28, 2022Microbiology

Impaired immune response drives age-dependent severity of COVID-19

J. Beer, S. Crotta, A. Breithaupt, A. Ohnemus, J. Becker, B. Sachs, L. Kern, M. Llorian, N. Ebert, F. Labroussaa, T. T. N. Tran, B. S. Trueeb, J. Jores, V. Thiel, M. Beer, , D. Schnepf

This study identifies impaired interferon responses as a cause of age-dependent COVID-19 severity and shows that combined IFN-γ and IFN-λ therapy can mitigate disease in aged mice.

bioRxiv · Apr 21, 2022Immunology