Author

M. Llorian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:development & morphogenesis· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Wack· 2 shared S. Crotta· 2 shared A. Adrian C. Hayday· 1 shared A. Breithaupt· 1 shared A. Jandke· 1 shared A. M. Mavrigiannaki· 1 shared A. Ohnemus· 1 shared A. Pavlova· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

A. Wack

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Epi-microRNA mediated metabolic reprogramming ensures affinity maturation

R. Nakagawa, M. Llorian, S. Varsani-brown, P. Chakravarty, J. M. Camarillo, D. Barry, R. George, N. P. Blackledge, G. Duddy, N. L. Kelleher, R. J. Klose, M. Turner, D. P. Calado

This study identifies miR-155's role in metabolic reprogramming of GC-B cells to support affinity maturation under hypoxic conditions.

bioRxiv · Jul 31, 2023Immunology

Impaired immune response drives age-dependent severity of COVID-19

J. Beer, S. Crotta, A. Breithaupt, A. Ohnemus, J. Becker, B. Sachs, L. Kern, M. Llorian, N. Ebert, F. Labroussaa, T. T. N. Tran, B. S. Trueeb, J. Jores, V. Thiel, M. Beer, , D. Schnepf

This study identifies impaired interferon responses as a cause of age-dependent COVID-19 severity and shows that combined IFN-γ and IFN-λ therapy can mitigate disease in aged mice.

bioRxiv · Apr 21, 2022Immunology

WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses

J. Biggs O'May, L. Vanes, L. de Boer, H. Hartweger, S. Kunzelmann, D. Hayward, M. Llorian, D. A. Lewis, R. Koechl, V. Tybulewicz

This study shows that WNK1-dependent water influx is essential for CD4+ T cell proliferation and T cell-dependent antibody responses.

bioRxiv · Mar 16, 2022Immunology

Tissue-intrinsic γδ T cells critically regulate Tissue-Resident Memory CD8 T cells

M. Munoz-Ruiz, M. Llorian, R. D'Antuono, A. Pavlova, A. M. Mavrigiannaki, D. Mckenzie, B. Garcia-Cassani, M. L. Iannitto, A. Jandke, D. Ushakov, A. Adrian C. Hayday

This study shows that tissue-intrinsic γδ T cells regulate TRM cells via a feedback loop involving IFNγ and PD-L1, affecting TRM function and cancer response.

bioRxiv · Jan 19, 2022 · PreprintImmunology

Type I and III interferons disrupt lung epithelial repair during recovery from viral infection

J. Major, S. Crotta, M. Llorian, T. M. McCabe, H. H. Gad, R. Hartmann, A. Wack

This study shows that type I and III interferons impair lung epithelial repair during viral infection recovery, increasing disease severity and bacterial susceptibility.

bioRxiv · May 5, 2020Immunology