B. Tomlinson

Staphylococcus aureus SigS induces expression of a regulatory protein pair that modulate its mRNA stability

This study identifies a regulatory protein pair, SroA and SroB, controlled by SigS in S. aureus, which modulate mRNA stability and virulence.

Phenogenomic characterization of a newly domesticated and novel species from the genus Verrucosispora

This study domesticates a novel marine Actinomycetes species, revealing genomic changes linked to growth, metabolism, and antibiotic potential during cultivation.

Assessing the role of cold-shock protein C: A novel regulator of Acinetobacter baumannii biofilm formation and virulence

This study identifies cold-shock protein C as a key regulator of biofilm formation and virulence in Acinetobacter baumannii through transcriptomic and functional analyses.

Resistance to decitabine and 5-azacytidine emerges from adaptive responses of the pyrimidine metabolism network

This paper identifies adaptive metabolic responses in pyrimidine metabolism as a mechanism of resistance to decitabine and 5-azacytidine, and shows that alternating these drugs with metabolic inhibitors can extend DNMT1 depletion and delay leukemia relapse.

MroQ is a Novel Abi-domain Protein That Influences Virulence Gene Expression in Staphylococcus aureus via Modulation of Agr Activity

This paper identifies MroQ as a novel Abi-domain protein in S. aureus that modulates Agr activity, affecting virulence gene expression and pathogenic outcomes.