Author

B. V. H. Hornung

Primary ORCID profile (0000-0001-7301-5228 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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B. V. H. HornungiD1 paper · Medicines Evaluation Board

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Assay:whole-genome sequencing· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:statistical model· 1

Frequent Co-Authors

E. J. Kuijper· 3 shared W. K. Smits· 3 shared C. Harmanus· 2 shared A. E. Sevilla Romeo· 1 shared A. M. Roseboom· 1 shared E. Terveer· 1 shared I. Boekhoud· 1 shared I. M. J. G. Bos-Sanders· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

E. J. Kuijper

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3 papers

Recent·Most cited

MicrobiologybioRxivJul 10, 2022

Carriage of three plasmids in a single human clinical isolate of Clostridioides difficile

A. M. Roseboom, Q. R. Ducarmon, B. V. H. Hornung…·W. K. Smits

The paper describes a C. difficile clinical isolate carrying three compatible plasmids and identifies functional replicons in two of them.

DOI 10.1016/j.plasmid.2022.102669

C. eleganswhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivMay 29, 2019

An in silico survey of Clostridioides difficile extrachromosomal elements

B. V. H. Hornung, E. J. Kuijper, W. K. Smits

This study identifies extrachromosomal elements in C. difficile strains using in silico analysis, finding 13% of strains contain 1-6 elements, including 6 novel plasmid families.

DOI 10.1099/mgen.0.000296

C. eleganswhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivMay 29, 2019

Plasmid-mediated metronidazole resistance in Clostridioides difficile

I. Boekhoud, B. V. H. Hornung, A. E. Sevilla Romeo…·W. K. Smits

This paper identifies a plasmid, pCD-METRO, as the first reported cause of plasmid-mediated metronidazole resistance in Clostridioides difficile, showing its global dissemination and horizontal transfer potential.

DOI 10.1038/s41467-020-14382-1

C. eleganswhole-genome sequencing

𝕏 PostBluesky