Author

I. M. J. G. Bos-Sanders

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

E. J. Kuijper· 3 shared W. K. Smits· 3 shared C. Harmanus· 2 shared I. M. Boekhoud· 2 shared A. E. Sevilla Romeo· 1 shared B. Spittal· 1 shared B. V. H. Hornung· 1 shared COMBACTE-CDI Consortium· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

E. J. Kuijper

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3 papers

Recent·Most cited

MicrobiologybioRxivNov 18, 2020

Heme is crucial for medium-dependent metronidazole resistance in clinical isolates of C. difficile

I. M. Boekhoud, I. Sidorov, S. Nooij…·European Study Group for Clostridioides difficile

The paper shows heme dependence in metronidazole resistance in C. difficile clinical isolates, linked to a SNP in hsmA and associated with a resistant lineage.

DOI 10.1093/jac/dkab097

C. elegansDNA methylation

𝕏 PostBluesky

MicrobiologyNature CommunicationsPeer-reviewedJan 30, 2020

Plasmid-mediated metronidazole resistance in Clostridioides difficile

I. Boekhoud, B. V. H. Hornung, A. E. Sevilla Romeo…·W. K. Smits

This paper identifies a plasmid, pCD-METRO, as the first reported cause of plasmid-mediated metronidazole resistance in Clostridioides difficile, showing its global dissemination and horizontal transfer potential.

DOI 10.1038/s41467-020-14382-1

C. eleganswhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivSep 21, 2018

Genome location dictates the transcriptional response to PolC-inhibition in Clostridium difficile

E. van Eijk, I. M. Boekhoud, E. J. Kuijper…·W. K. Smits

This study shows that genome location influences the transcriptional response to PolC-inhibition in C. difficile, with origin-proximal genes being more upregulated.

DOI 10.1128/aac.01363-18

C. eleganswhole-genome sequencing

𝕏 PostBluesky