B. W. M. de Wildt

This study develops a dialysis-based cell culture system for osteoblast-osteoclast cocultures, showing increased osteoblastic and osteoclastic activity compared to standard methods.

This study evaluates how culture variables affect in vitro human bone remodeling models using a design of experiments approach to improve reproducibility and translatability.

This study evaluates how curvature and directional fluid flow affect three-dimensional bone-like tissue growth and organization using human mesenchymal stromal cells in a concave channel scaffold.

This study develops an in vitro human bone defect model to evaluate material-driven regeneration using tissue engineering, observing vascular-like network growth and bone-like tissue formation.

This study tunes an in vitro 3D osteoblast-osteoclast co-culture model to simulate bone formation, resorption, and equilibrium states using different culture media and monocyte seeding densities.

This study develops a bioinspired silk fibroin-based scaffold for in vitro bone remodeling that supports osteoclast and osteoblast interactions, reducing animal experiments and advancing drug testing for osteoporosis.

This study compares fetal bovine serum (FBS) and human platelet lysate (hPL) as supplements in in vitro bone remodeling models, finding hPL supports both osteoclast and osteogenic differentiation with concentration-dependent effects.

This study systematically reviews osteoblast-osteoclast co-culture studies to provide databases for methods, outcomes, and parameters, enabling comparison and validation of research.