Author

B. Wiedenmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Assay:imaging· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

C. Groetzinger· 3 shared S. Exner· 2 shared S. Sachindra· 2 shared A. Chouchane· 1 shared A. Klussmeier· 1 shared A. Kollar· 1 shared A. Perren· 1 shared C. A. Kunze· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

C. Groetzinger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Patient-derived tumoroids of advanced high-grade neuroendocrine neoplasms mimic patient chemotherapy responses and guide the design of personalized combination therapies

S. L. April-Monn, K. Detjen, P. Kirchner, K. Braeutigam, M. A. Trippel, T. Grob, C. Statzer, R. S. Maire, A. Kollar, A. Chouchane, C. A. Kunze, D. Horst, M. C. Sadowski, J. Schrader, I. Marinoni, , A. Perren

The paper develops patient-derived tumoroids to predict chemotherapy responses and identify synergistic drug combinations for high-grade GEP-NEN.

bioRxiv · Dec 10, 2022 · PreprintCancer Biology

Secretin receptor as a target in gastrointestinal cancer: expression analysis and ligand development

A. Klussmeier, S. Aurich, L. Niederstadt, B. Wiedenmann, C. Groetzinger

This study analyzes SCTR expression in cancers and identifies key residues for secretin binding and activation, aiming to develop stable analogs for imaging and therapy.

bioRxiv · Jan 31, 2022Cancer Biology

SPECT/CT imaging, biodistribution and radiation dosimetry of a 177Lu-DOTA-integrin αvβ6 cystine knot peptide in a pancreatic cancer xenograft model

S. Sachindra, T. Hellberg, S. Exner, S. Prasad, N. Beindorff, S. Rogalla, R. Kimura, S. S. Gambhir, B. Wiedenmann, C. Groetzinger

This study evaluates a 177Lu-labeled integrin αvβ6-targeting knottin peptide for imaging and therapy of pancreatic cancer using xenograft models, showing high tumor accumulation and moderate kidney uptake.

bioRxiv · Mar 23, 2021Cancer Biology

AGTR1 is overexpressed in neuroendocrine neoplasms, regulates secretion and may serve as a target for molecular imaging and therapy

S. Exner, C. Schuldt, S. Sachindra, J. Du, I. Heing-Becker, K. Licha, B. Wiedenmann, C. Groetzinger

This study identifies AGTR1 as an overexpressed target in neuroendocrine neoplasms, showing its role in secretion and potential for imaging and therapy.

bioRxiv · Nov 26, 2019Cancer Biology