N. Beindorff

SPECT/CT imaging, biodistribution and radiation dosimetry of a 177Lu-DOTA-integrin αvβ6 cystine knot peptide in a pancreatic cancer xenograft model

This study evaluates a 177Lu-labeled integrin αvβ6-targeting knottin peptide for imaging and therapy of pancreatic cancer using xenograft models, showing high tumor accumulation and moderate kidney uptake.

CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

This paper develops CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer, showing high specificity and affinity in vivo.

Increasing molar activity by HPLC purification improves 68Ga-DOTA-NAPamide tumor accumulation in a B16/F1 melanoma xenograft model

This study shows that HPLC purification of 68Ga-DOTA-NAPamide increases tumor uptake in B16/F1 melanoma xenografts by removing unlabeled peptide, enhancing molar activity and specific binding.