S. Prasad

Whole Genome Sequencing and Assembly of the House Sparrow, Passer domesticus

The paper provides a high-quality whole genome sequence and assembly for the house sparrow, Passer domesticus, which serves as a reference for comparative and population genomic studies.

Relationship between luteal size and plasma progesterone concentration in pregnant and non-pregnant Indian crossbred dairy cows

This study examines the relationship between luteal size parameters and plasma progesterone concentration in pregnant and non-pregnant Indian crossbred cows, finding luteal area is a better indicator of corpus luteum function.

Probing single cell fermentation flux and intercellular exchange networks via pH-microenvironment sensing and inverse modeling

This study quantifies single cell fermentation fluxes and intercellular exchange networks using pH microenvironment sensing and inverse modeling in mixed cancer and fibroblast cultures, revealing heterogeneous proton trafficking and a crossover from hub-driven to dipolar exchange phases.

Protein kinase D promotes prostate cancer cell bone metastasis by positively regulating Runx2 in a MEK/ERK1/2-dependent manner

This study shows that PKD promotes prostate cancer bone metastasis by regulating Runx2 via MEK/ERK1/2 signaling, and inhibiting PKD reduces metastasis in mice.

SPECT/CT imaging, biodistribution and radiation dosimetry of a 177Lu-DOTA-integrin αvβ6 cystine knot peptide in a pancreatic cancer xenograft model

This study evaluates a 177Lu-labeled integrin αvβ6-targeting knottin peptide for imaging and therapy of pancreatic cancer using xenograft models, showing high tumor accumulation and moderate kidney uptake.

Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia

The paper identifies GOT2-catalyzed mitochondrial aspartate synthesis as essential for pancreatic tumor cell proliferation under hypoxia, but this dependency is bypassed by hypoxia-induced macropinocytosis.

Plastic ingestion in Asian elephants in the forested landscapes of Uttarakhand, India

This study documents plastic and other non-biodegradable waste in Asian elephant dung in Uttarakhand, India, finding higher plastic prevalence in forest interiors than edges.

CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer

This paper develops CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer, showing high specificity and affinity in vivo.

Increasing molar activity by HPLC purification improves 68Ga-DOTA-NAPamide tumor accumulation in a B16/F1 melanoma xenograft model

This study shows that HPLC purification of 68Ga-DOTA-NAPamide increases tumor uptake in B16/F1 melanoma xenografts by removing unlabeled peptide, enhancing molar activity and specific binding.

Detection of acute TLR-7 agonist-induced hemorrhagic myocarditis in mice by refined multi-parametric quantitative cardiac MRI.

This study identifies hemorrhagic myocarditis in mice induced by TLR-7 agonist using multi-parametric cardiac MRI, showing distinct T1, T2, and T2* relaxation patterns.