PhysiologybioRxiv
Loss And Gain Of Function Experiments Implicate TMEM18 As A Mediator Of The Strong Association Between Genetic Variants At Human Chromosome 2p25.3 And Obesity
R. Larder, M. F. M. Sim, P. Gulati…·A. P. Coll
The paper identifies TMEM18 as a mediator of genetic variants at 2p25.3 associated with obesity through loss and gain of function experiments in mice.
DOI 10.1073/pnas.1707310114