Auranofin inhibits virulence in Pseudomonas aeruginosa
L. Z. W. Tan, J. K. H. Yam, Z. Hong, M. M. S. Salido, B. Y. Woo, S. F. Y. Li, L. Yang, M. Givskov, S.-S. Chng
This study shows that auranofin inhibits virulence in Pseudomonas aeruginosa by targeting Vfr, reducing quorum sensing and Type IV pili, and synergizing with colistin to eliminate biofilms.
bioRxiv · May 13, 2020 · PreprintMicrobiology