Alpha-synuclein supports interferon stimulated gene expression in neurons
Aaron R. Massey, Brendan Monogue, Yixi Chen, Kelsey E. Lesteberg, Michaela E. Johnson, Liza Bergkvist, Jennifer A. Steiner, Jiyan Ma, Ravi Mahalingam, B.K. Kleinschmidt-Demasters, Martha L. Escobar Galvis, Patrik Brundin, Tilo Kunath, J. David Beckham
This study shows alpha-synuclein is required for interferon-stimulated gene expression in neurons during RNA virus infection and links it to phosphorylated S129-asyn pathology.
bioRxiv · Apr 25, 2020 · PreprintNeuroscience