Author

John David Beckham

The University of Texas Southwestern Medical CenterORCID 0000-0001-9305-2683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Brendan MonogueiD· 2 shared Camille Merrick· 2 shared Dustin L. Heiden· 2 shared Aaron R. Massey· 1 shared Alayna Rosales· 1 shared B.K. Kleinschmidt-Demasters· 1 shared Imali Kegode· 1 shared Jennifer A. SteineriD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

Brendan MonogueORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 29, 2026

Structure informed xrRNA2 mutations in Zika virus provide a roadmap for vaccine development

Camille Merrick, Imali Kegode, Sarah Leach…·John David Beckham

This study introduces structure-informed mutations in ZIKV xrRNA2 to attenuate the virus and evaluate its potential as a vaccine, finding reduced virulence and complete protection in mice.

DOI 10.64898/2026.05.27.728262

mouseexperimental assay

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ImmunologyThe Journal of ImmunologyPeer-reviewedMay 1, 2026

Myeloid cell IL-15 production in the brain supports Bystander CD8+ T-Cell Neuropathic Immune Responses following Virus infection

Jennifer N. Berger, Alayna Rosales, Dustin L. Heiden…·Leslie J. Berg

1 citation

mouseproteomics

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NeurosciencebioRxivPreprintApr 25, 2020

Alpha-synuclein supports interferon stimulated gene expression in neurons

Aaron R. Massey, Brendan Monogue, Yixi Chen…·J. David Beckham

This study shows alpha-synuclein is required for interferon-stimulated gene expression in neurons during RNA virus infection and links it to phosphorylated S129-asyn pathology.

4 citations

humanmouse

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