Jennifer A. Steiner

This study shows that neuroinflammation occurs early in a mouse model of prodromal Parkinson's disease before neuronal loss, linking Syn pathology to olfactory dysfunction.

This study profiles DNA methylation in COVID-19 patients and finds hypomethylation linked to neurological pathways in severe cases.

The paper identifies that Tet2 loss promotes ciliogenesis and reduces α-synuclein pathology in Parkinson's disease models.

This study investigates how alpha-synuclein aggregation in the basolateral amygdala affects glutamatergic transmission, finding that it selectively disrupts cortico-BLA synapses.

The paper shows that experimental colitis increases alpha-synuclein accumulation in the gut and brain, linking intestinal inflammation to Parkinson's disease pathology.

This study shows that T cells reduce phosphorylated α-synuclein pathology in a mouse model of α-synucleinopathy.

The paper tests if inhibiting the mitochondrial pyruvate carrier reduces synucleinopathy in PD models but finds no effect on Syn aggregation or neurodegeneration.

This study shows that α-Synuclein seeding in the olfactory bulb leads to altered odor-evoked neural activity in the olfactory system.

This study shows alpha-synuclein is required for interferon-stimulated gene expression in neurons during RNA virus infection and links it to phosphorylated S129-asyn pathology.

This study shows that loss of one Engrailed1 allele in mice increases α-synuclein aggregation after PFF injection, suggesting a role for En1 in PD pathology.